This process can result in a good misclassification out-of BP groups and you will establish dilution bias, possibly underestimating real relationships

This process can result in a good misclassification out-of BP groups and you will establish dilution bias, possibly underestimating real relationships

In the current study, the association of new BP categories with risk of incident CVD was more evident in young adults aged <40 years than in the older subjects, which is in line with earlier studies that also reported a stronger association between BP and CVD outcomes in middle?aged compared with elderly populations. 8 , 46 , 51 , 52 , 53 The reasons for the stronger associations in young adults are unclear.

The outcome away from BP on the risk of CVD is generally diluted with growing many years once the the prevalence out of high BP and you will other CVD risk situations also be more common with age

Into the South Korea, the fresh Korean Area of Blood circulation pressure computed to make use of the earlier blood circulation pressure standards out-of systolic BP/diastolic BP ? mm Hg on account of insufficient obvious research for additional take advantage of reducing the hypertension threshold so you’re able to mm Hg to have Koreans. 54 , 55 According to the Korean Blood circulation pressure Facts Layer 2018, exactly how many people diagnosed with blood pressure levels improved away from 3 billion within the 2002 to eight.9 billion in 2016, with only 5.7 million people with suitable and you can chronic antihypertensive therapy from inside the 2016. 56 The treatment rate enhanced of twenty two% within the 1998 so you’re able to 59% when you look at the 2007 also to 61% for the 2016, therefore the handle speed improved regarding 5% during the 1998 to help you 41% for the 2007 also to 49% during the 2016. 56 In the research conducted recently utilizing the Korean Federal Health and Diet Examination Questionnaire, the fresh incidence out of blood pressure levels and also the amount of adults who want antihypertensive medication will be enhanced, are comparable with other countries. 55 , 57 , 58 Based on latest education dealing with implementation of the fresh guidelines in several nations, like the Us, China, and you can Korea, the fresh new 2017 ACC/AHA blood circulation pressure recommendations will significantly enhance the incidence of hypertension and you may how many clients who are in need of antihypertensive cures initiation and the ones who are in need of procedures intensification international. 57 , 58 , 59 , sixty , 61 , 62 Within the research conducted recently regarding the Federal Health and Nourishment Examination Questionnaire, depending on the 2017 ACC/AHA tip, weighed against new Seventh Mutual National Committee rule, the incidence off blood circulation pressure has grown of 30.9% to help you forty five.6%, new percentage of You adults suitable for antihypertensive medication has increased away from 34.3% to thirty-six.2%, and you can 53.4% folks people getting antihypertensive procedures you prefer way more rigorous decline in the BP. 59 In the event of Asia, adoption of 2017 ACC/AHA blood pressure guidelines carry out resulted in increment about frequency out of blood pressure of twenty-five% so you’re able to fifty%. 63 It ought to be evaluated if the such alterations in the latest diagnostic threshold and you can healing goals of so you can mm Hg do boost BP control as well as relevant consequences. Upcoming studies are and wanted to confirm this new connection between BP and CVD chance about younger society which have diverse ethnicity and you will to choose in case the exposure/work for proportion to possess treatment is beneficial within reasonable?risk classification.

This and you can gender standardization are performed utilising the direct strategy to your ages construction of the Korean population, aged 20 to help you 80 many years, in the year 2010

The strengths of our study are its cohort study design, the large sample size, the use of carefully standardized clinical procedures, and the almost complete follow?up for CVD events, as the National Health Insurance collects all medical services use covering the entire Korean population. This study also has several limitations. First, as with most previous studies, the determination of BP was based on a single?day measurement, although 3 readings were taken. Second, we did not incorporate changes in BP categories and other covariates during follow?up. Third, health behaviors were assessed via a self?administered structured questionnaire used in health checkup programs in Korea, as part of the National Health Insurance plan. Measurement errors in these variables may introduce some degree of residual confounding, similar to most epidemiologic studies. Fourth, we used the Pooled Cohorts Equations in all participants; however, it was not validated in adults aged <40 years. Finally, this is an opportunistic cohort of individuals, who self?presented for the health examination, and hence is not a representative sample of low cardiovascular risk young adults in the community. The study population of this cohort was relatively highly educated, young to middle?aged Korean adults with high accessibility to healthcare resources. We compared our study population with a representative sample of the general Korean population (the Korea National Health and Nutrition Examination Survey). The age? and sex?standardized prevalence of hypertension (defined as systolic BP ?140 mm Hg, diastolic BP ?90 mm Hg, or the use of antihypertensive medication), type 2 diabetes mellitus (defined as fasting serum glucose level ?126 mg/dL or the use of blood glucose–lowering agents), obesity (body mass index ?25 kg/m 2 ), and current smoker was lower than those of the general population (16.6% versus 29.1%, 9.3% versus 10.5%, 27.6% versus 31.5%, and 16.8% versus 26.5%, respectively), indicating that our study population may be healthier than the general Korean population. Thus, our findings might not be generalizable to other ethnic groups or populations with different age, demographic, diet, and health behavior characteristics.

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