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- Schmidt-Kastner R, Szymas J. Immunohistochemistry of glial fibrillary acidic protein, vimentin and S-100 protein for examine of astrocytes in hippocampus of rat.
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Brodkey JA, Gates MA, Laywell ED, Steindler DA. The complicated nature of interactive neuroregeneration-related molecules. Rudge JS, Silver J. Inhibition of neurite outgrowth on astroglial scars in vitro. Rose G, Lynch G, Cotman CW. Hypertrophy and redistribution of astrocytes within sex cam the deafferented dentate gyrus. Davies JA, Cook GM, Stern CD, Keynes RJ. Isolation from chick somites of a glycoprotein fraction that causes collapse of dorsal root ganglion progress cones.
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After a penetrating lesion within the central nervous system, astrocytes enlarge, divide, and participate in creating an setting that adversely impacts neuronal regeneration. We have recently shown that the neural cell adhesion molecule (N-CAM) partially inhibits the division of early postnatal rat astrocytes in vitro. Animals were lesioned within the cerebral cortex, hippocampus, or striatum with a Hamilton syringe and needle at defined stereotaxic positions. On one aspect, the lesions had been concomitantly infused with N-CAM or with one of the N-CAM-related molecules. As a management, a peptide of the identical composition as the N-CAM decapeptide however of random sequence was infused on the contralateral facet of the mind. We persistently discovered that the inhabitants of dividing astrocytes was significantly smaller on the side during which N-CAM or one of many N-CAM-related molecules was infused than on the opposite aspect.
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